About fahr's disease

What is fahr's disease?

Familial idiopathic basal ganglia calcification (FIBGC) is a rare neurological disorder characterized by the presence of abnormal calcium deposits (calcifications) of unknown cause. Associated symptoms include progressive deterioration of cognitive abilities (dementia), loss of contact with reality (psychosis), mood swings and loss of acquired motor skills. As the condition progresses, paralysis may develop that is associated with increased muscle stiffness (rigidity) and restricted movements (spastic paralysis). Additional abnormalities may include relatively slow, involuntary, continual writhing movements (athetosis) or chorea, a related condition characterized by irregular, rapid, jerky movements.

What are the symptoms for fahr's disease?

Dementia symptom was found in the fahr's disease condition

You may have no symptoms at all. But if you do, there are usually two types: either movement-related or psychiatric. The exact symptoms depend on which part of your brain is affected.

Movement symptoms:

  • Clumsiness
  • Walking unsteadily
  • Talking more slowly than usual, or slurring your words
  • Difficulty swallowing
  • Involuntary movement of arms or legs
  • Cramped muscles
  • Stiff arms and legs (called spasticity)
  • Tremors, muscle stiffness, lack of facial expression

Psychiatric symptoms:

  • Poor concentration
  • Lapses in memory
  • Mood changes
  • Psychosis, or being out of touch with reality
  • Dementia

Other symptoms:

  • • Tiredness
  • • Migraines
  • • Seizures
  • • Vertigo, or dizziness
  • • Not being able to control when you urinate (called urinary incontinence)
  • • Impotence

What are the causes for fahr's disease?

Basal ganglia calcification sometimes happens when you age, but many times comes from genes passed to you by your parents. You only need one faulty gene from one parent to get the illness. Your parents may have symptoms of it, but sometimes they don’t.

build-up in your basal ganglia can also happen because of infection, problems with your parathyroid gland, and for other reasons. When it happens this way, it is also known as basal ganglia calcification, but is different from the genetic form of the disease.

What are the treatments for fahr's disease?

There is no cure, but there is treatment for the symptoms. For example, if you have seizures, certain anti-epileptic medicines can help. Or if you have migraines, you can take medicine to both prevent and treat them.

If you are anxious or depressed, see your doctor. There are medicines to help with mood issues.

If you have this condition, it’s a good idea to see your doctor or specialist every year to see if it’s changed or advanced.

What are the risk factors for fahr's disease?

Risk factors of Fahr’s disease:

1. Fahr's disease is a hereditary genetic condition marked by abnormal calcium deposits in parts of the brain that regulate movement.
2. Basal ganglia, cerebral, and cortical regions (parts of the brain) have calcium deposits that cause atrophy.
3. Motor and mental problems result from the considerable neuron (brain cell) loss caused by this mineral deposit.
4. There is a paucity of molecular and genetic evidence about the molecular genetics of Fahr's disease.
5. However, one of the genes responsible for idiopathic basal ganglia calcification has been identified as IBGC1.
6. Chromosomes 8 and 2 are found to be a second locus for the genetic pathogenesis of Fahr's disease.
7. Fahr's disease typically affects people in their 40s and 50s, though it can also strike children or teenagers. The prevalence of the disease is lower than 1 in 1,000,000.
8. The body's metabolism, particularly the serum calcium content, is disrupted by endocrine diseases, which can result in excessive calcification of brain tissue.

Symptoms
Deterioration of motor function,Dementia,Seizures,Headache
Conditions
Spasticity,Gait disorder,Speech impairment,Dementia,Parkinsonism,Chorea,Tremors,Dystonia,Myoclonus,Coma
Drugs
Carbamazepine,Lithium

Is there a cure/medications for fahr's disease?

Fahr's disease is a hereditary genetic condition marked by abnormal calcium deposits in parts of the brain that regulate movement. Basal ganglia, cerebral, and cortical regions (parts of the brain) have calcium deposits that cause atrophy. Motor and mental problems result from the considerable neuron (brain cell) loss caused by this mineral deposit.

There is a paucity of molecular and genetic evidence about the molecular genetics of Fahr's disease. However, one of the genes responsible for idiopathic basal ganglia calcification has been identified as IBGC1. Chromosomes 8 and 2 are found to be a second locus for the genetic pathogenesis of Fahr's disease. Fahr's disease typically affects people in their 40s and 50s, though it can also strike children or teenagers. The prevalence of the disease is lower than 1 in 1,000,000.

There is no cure available for this disease. Treatments are, however, available.

Fahr syndrome treatment

1. Fahr disease has no known specific treatments as of yet.
2. Treatment options for this condition's symptoms, including movement problems, seizures, anxiety, depression, psychosis, and urine incontinence, include medications.
3. Few people have reported receiving bisphosphonates outside of their prescribed dosage.
4. Each patient's symptoms are addressed specifically through treatment.
5. Any person with Fahr's disease has an unpredictable and difficult-to-predict prognosis.

Symptoms
Deterioration of motor function,Dementia,Seizures,Headache
Conditions
Spasticity,Gait disorder,Speech impairment,Dementia,Parkinsonism,Chorea,Tremors,Dystonia,Myoclonus,Coma
Drugs
Carbamazepine,Lithium

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