Symptoms of hereditary neuropathy depend on the group of nerves affected. They can affect the motor, sensory, and autonomic nerves. Sometimes, they affect more than one nerve group. For instance, Charcot-Marie-Tooth (CMT) disease, one of the most common types of hereditary neuropathies, affects the motor and sensory nerves.
Hereditary neuropathies can have similar symptoms. Some of the most common symptoms include:
- Sensory symptoms: Pain, tingling, or numbness, often in the hands and feet.
- Motor symptoms: Muscle Weakness and loss of mass (muscle atrophy), often in the feet and lower legs.
- Autonomic symptoms: Impaired sweating, or low blood pressure after standing up from sitting or lying down.
- Physical deformities: High foot arches, hammer-shaped toes, or a curved spine (scoliosis).
Hereditary neuropathy symptoms can range in intensity from mild to severe. In some cases, symptoms are so mild that the disorder goes undiagnosed and untreated for a long time.
Symptoms don’t always appear at birth or during childhood. They can appear during middle age or even later in life.