Opthalmoneuromyelitis, also known as Devic disease, is an acquired condition triggered by autoimmune reactions and certain microbial infections. However, some studies suspect the involvement of genetic factors. It is a rare chronic demyelinating disorder that affects the optic nerve and spinal cord. There are two forms: monophasic and relapsing. Monophasic occurs once that lasts for 30 to 60 days. Whereas it recurs in a relapsing type, as episodes separated by a period of recovery lasting months or years apart.
Few studies have shown links between some factors and the disease, while some studies are still underway to establish risk factors for the disease. Some evident factors are as follows:
1. Autoimmune disorders: A few studies have recorded the disease in patients with familial history of autoimmune disorders. Therefore, it is considered a risk factor.
2. Lifestyle factors: With the backing of pieces of evidence produced by a study conducted in 2018, some lifestyle factors have been associated with the disease.
They include long-term smoking, passive smoking, and long-term consumption of whiskey or vodka. They are risk factors for immunoglobulin G positivity. In addition, there is a link between smoking and the development of autoantibodies, which induce autoimmunity.
3. High levels of saturated fatty acids: A study has shown a link between high consumption of bad fats (animal and trans fats) and devic disease.
Eye pain,Loss of vision,Colors appearing faded or less vivid,Weakness in the arms and legs,Pain in the arms or legs – described as sharp, burning, shooting or numbing,Increased sensitivity to cold and heat,Tight and painful muscle spasms in the arms and legs,Vomiting,Bladder, bowel, and sexual problems
The immune system damages the spinal cord and the nerves of the eyes (optic nerves)
Steroids to reduce the inflammation,Medicine to suppress your immune system and ease your symptoms, such as azathioprine, mycophenolate or methotrexate,Rituximab, a newer type of medicine to reduce inflammation