Takatsuki syndrome, also known as POEMS syndrome, is a blood disorder that occurs in the body. In this uncommon circumstance, abnormal plasma cells cause an increase in antibody protein levels in the blood. Too many of these proteins in the blood can cause nerve damage and the malfunction of several organ systems.
POEMS syndrome is uncommon and can be fatal. Osteosclerotic myeloma, Crow-Fukase syndrome, and Takatsuki syndrome are other names for it.
POEMS syndrome treatment focuses on symptom management. Therapy may consist of:
1. Chemotherapy: Anti-cancer medications will either slow or destroy the aberrant plasma cells. Treatment is comparable to that of multiple myeloma, a kind of plasma cell malignancy. These treatments are exceedingly successful and, in most cases, well tolerated, with few adverse effects. Immunotherapy medications assist your immune system in killing off the harmful plasma cells
2. Radiation therapy: High amounts of radiation are used by doctors to kill harmful plasma cells.
3. Physical therapy: This treatment may aid in mobility concerns caused by neuropathy.
4. Other medicines Steroids and/or diuretics (to reduce swelling) may be prescribed as well.
Numbness, tingling and weakness in your legs,Enlarged spleen, liver or lymph nodes,Abnormal hormone levels,Abnormal bone marrow cells,Skin changes
Steroids and/or diuretics