The neurological condition known as infantile epileptic encephalopathy is characterised by seizures. The disease typically manifests in the form of epileptic seizures in neonates within the first three months of life. Infants may develop partial seizures, myoclonic seizures, and tonic seizures (which induce stiffness of the bodily muscles, usually those in the back, legs, and arms) (which cause jerks or twitches of the upper body, arms, or legs). The majority of newborns with the disease exhibit anatomical abnormalities or partial or complete underdevelopment of the brain hemispheres. Some cases are brought on by genetic alterations in multiple genes or metabolic problems. There are multiple instances when the cause is unknown.
Symptoms of infantile epileptic encephalopathy
Here are symptoms for the infantile epileptic encephalopathy-
Age of onset refers to the typical age at which a disease first manifests its symptoms. For some diseases, the age of onset might vary, and a doctor may use this information to make a diagnosis. Some disorders may show symptoms at one particular age or at numerous different ages. Other diseases can manifest their symptoms at any point in a person's life. Individuals may experience various variations of these symptoms. Symptoms can range from moderate to severe, and some people may experience them more frequently than others.
Prognosis for infantile epileptic encephalopathy
Children with severe epileptic encephalopathy frequently experience early mortality, which is frequently brought on by seizures, chest infections, and pneumonia. Children who have frequent seizures go through developmental regression and lose learnt skills. A lifelong intellectual handicap is probable for those who are severely impacted by epileptic encephalopathy.
About 75% of epileptic encephalopathy patients will remain susceptible to West syndrome, another age-dependent encephalopathy. Tonic spasms, severe and ongoing epileptic activity, and severe mental retardation are shared features of epileptic encephalopathy and West syndrome. Typically, West syndrome appears three months after birth.