Foodborne botulism Signs and symptoms of foodborne botulism typically begin between 12 and 36 hours after the toxin gets into your body. But, depending on how much toxin was consumed, the start of symptoms may range from a few hours to a few days. Signs and symptoms of foodborne botulism include: Difficulty swallowing or speaking Dry mouth Facial weakness on both sides of the face Blurred  Read More

Creutzfeldt-Jakob disease is marked by rapid mental deterioration, usually within a few months. Initial signs and symptoms typically include: Personality changes Anxiety Depression Memory loss Impaired thinking Blurred vision or blindness Insomnia Difficulty speaking Difficulty swallowing Sudden, jerky movements As the disea  Read More

Guillain-Barre syndrome often begins with tingling and weakness starting in your feet and legs and spreading to your upper body and arms. In about half of people with the disorder, symptoms begin in the arms or face. As Guillain-Barre syndrome progresses, muscle weakness can evolve into paralysis. Signs and symptoms of Guillain-Barre syndrome may include: Prickling, pins and needles sensations in your fingers, toes, ankl  Read More

Idiopathic basal ganglia calcification is a hereditary, genetic condition marked by abnormal calcium deposits in parts of the brain that regulate movement. Basal ganglia, cerebral, and cortical regions (parts of the brain) have calcium deposits that cause atrophy. Motor and mental problems result from the considerable neuron (brain cell) loss caused by this mineral deposit. There is a paucity of molecular and gene  Read More

Kennedy disease is a rare, X-linked slowly progressive neuro-muscular disorder. Kennedy disease is typically an adult-onset disease, where symptoms occur mainly between the ages of 20 and 50. The disease is characterized by symptoms such as muscle weakness and cramps in the arms, legs, and facial area, enlarged breasts, and difficulty with speaking and swallowing (dysphagia). Kennedy disease affects fewer than 1 in 150,000 males and does not t  Read More

Symptoms of Motor Neuron Disease are as follows:1. Amyotrophic Lateral Sclerosis: ALS influences your upper as well as your lower motor neurons. Gradually, your control over the muscles that aid you in walking, speaking, chewing, swallowing and breathing is lost. They grow weaker and waste away as time passes. You could experience stiffness and twitches in the muscles.2. Primary Lateral Sclerosis: PLS o  Read More

The spinal muscular atrophies (SMAs), are characterized by degeneration of nerve cells (motor nuclei) within the lowest region of the brain (lower brainstem) and certain motor neurons in the spinal cord (anterior horn cells) leading to muscle weakness of the truncal, and extremity muscles initially, followed by chewing, swallowing and breathing difficulties. Motor neurons are nerve cells that transmit nerve impulses from the spinal cord or bra  Read More

Subacute spongiform encephalopathy is also known as Creutzfeldt-Jakob disease (CJD), which is a degenerative brain condition that causes dementia and, eventually, death. Symptoms of Creutzfeldt-Jakob disease may resemble those of dementia-like brain illnesses, such as Alzheimer's. However, Creutzfeldt-Jakob disease normally advances much faster. CJD first gained public notice in the 1990s, when several persons in  Read More

Usually, faulty modifications (mutations) in the EZH2 gene result in Wallenberg syndrome. The EZH2 gene functions wrongly as a result of these detrimental alterations. The EZH2 gene has the ability to methylate, or switch on and off, other genes. The fact that Wallenberg syndrome affects numerous body systems is due to the influence of the EZH2 gene on the operation of numerous other genes. However, it is unkn  Read More

X-linked myotubular myopathy (XLMTM) is a rare genetic neuromuscular disorder that is characterized by muscle weakness that can range from mild to profound. Symptoms are often present at birth, but may first develop during infancy or early childhood. In rare cases, symptoms may not develop until later, even adulthood. Common symptoms include mild to profound muscle weakness, diminished muscle tone (hypotonia or "floppiness"), feeding difficult  Read More