- Endovascular Thrombectomy Following Acute Ischemic Stroke: A Single-Center Case Series and Critical Review of the Literature
Acute ischemic stroke (AIS) due to thrombo-embolic occlusion in the cerebral vasculature is a major cause of morbidity and mortality in the United States and throughout the world. Although the prognos... Read More
- Stroke Neuroprotection: Targeting Mitochondria
Stroke is the fourth leading cause of death and the leading cause of long-term disability in the United States. Blood flow deficit results in an expanding infarct core with a time-sensitive peri-infar... Read More
- NADPH Oxidase as a Therapeutic Target for Neuroprotection against Ischaemic Stroke: Future Perspectives
Oxidative stress caused by an excess of reactive oxygen species (ROS) is known to contribute to stroke injury, particularly during reperfusion, and antioxidants targeting this process have resulted in... Read More
- Neural Repair and Neuroprotection with Stem Cells in Ischemic Stroke
Stem cells have been touted as a potential source of cells for repair in regenerative medicine. When transplanted into the central nervous system, stem cells have been shown to differentiate into neur... Read More
- Ethanol Modulates Spontaneous Calcium Waves in Axonal Growth Cones in Vitro
In developing neurons the frequency of long duration, spontaneous, transient calcium (Ca2+) elevations localized to the growth cone, is inversely related to the rate of axon elongation and increases s... Read More
- Human Temporal Cortical Single Neuron Activity during Language: A Review
Findings from recordings of human temporal cortical single neuron activity during several measures of language, including object naming and word reading are reviewed and related to changes in activity... Read More
- Mechanisms Underlying Auditory Hallucinations Understanding Perception without Stimulus
Auditory verbal hallucinations (AVH) are a common phenomenon, occurring in the healthy population as well as in several mental illnesses, most notably schizophrenia. Current thinking supports a spec... Read More
- Involvement of Sphingolipids in Ethanol Neurotoxicity in the Developing Brain
Ethanol-induced neuronal death during a sensitive period of brain development is considered one of the significant causes of fetal alcohol spectrum disorders (FASD). In rodent models, ethanol triggers... Read More
- Long-Lasting Neural Circuit Dysfunction Following Developmental Ethanol Exposure
Fetal Alcohol Spectrum Disorder (FASD) is a general diagnosis for those exhibiting long-lasting neurobehavioral and cognitive deficiencies as a result of fetal alcohol exposure. It is among the most c... Read More
- Impact of Repetitive Transcranial Magnetic Stimulation (rTMS) on Brain Functional Marker of Auditory Hallucinations in Schizophrenia Patients
Several cross-sectional functional Magnetic Resonance Imaging (fMRI) studies reported a negative correlation between auditory verbal hallucination (AVH) severity and amplitude of the activations durin... Read More
- Differential Effects of Chronic and Chronic-Intermittent Ethanol Treatment and Its Withdrawal on the Expression of miRNAs
Chronic and excessive alcohol misuse results in changes in the expression of selected miRNAs and their mRNA targets in specific regions of the human brain. These expression changes likely underlie the... Read More
- Changes in Oscillatory Brain Networks after Lexical Tone Training
Learning foreign speech contrasts involves creating new representations of sound categories in memory. This formation of new memory representations is likely to involve changes in neural networks as r... Read More
- Neurovascular Coupling of the Posterior Cerebral Artery in Spinal Cord Injury: A Pilot Study
Purpose: To compare neurovascular coupling in the posterior cerebral artery (PCA) between those with spinal cord injury (SCI) and able bodied (AB) individuals. Methods: A total of seven SCI and seven ... Read More
- Effects of Lifelong Ethanol Consumption on Brain Monoamine Transmitters in Alcohol-Preferring Alko Alcohol (AA) Rats
The purpose of the present study was to examine the combined effects of aging and lifelong ethanol exposure on the levels of monoamine neurotransmitters in different regions of the brain. This work is... Read More
- From Neural Plate to Cortical Arousal A Neuronal Network Theory of Sleep Derived from in Vitro Model Systems for Primordial Patterns of Spontaneous Bioelectric Activity in the Vertebrate Central Nervous System
In the early 1960s intrinsically generated widespread neuronal discharges were discovered to be the basis for the earliest motor behavior throughout the animal kingdom. The pattern generating system i... Read More
- The Health Benefits and Challenges of Exercise Training in Persons Living with Schizophrenia: A Pilot Study
Background: In addition to the hallmark cognitive and functional impairments mounting evidence indicates that schizophrenia is also associated with an increased risk for the development of secondary c... Read More
- Multilingualism and fMRI: Longitudinal Study of Second Language Acquisition
BOLD fMRI is often used for the study of human language. However, there are still very few attempts to conduct longitudinal fMRI studies in the study of language acquisition by measuring auditory comp... Read More
- Neuroprotective Mechanisms of Taurine against Ischemic Stroke
Ischemic stroke exhibits a multiplicity of pathophysiological mechanisms. To address the diverse pathophysiological mechanisms observed in ischemic stroke investigators seek to find therapeutic strate... Read More
- Congenital Unilateral Deafness Affects Cerebral Organization of Reading
It is known that early sensory deprivation modifies brain functional structure and connectivity. The aim of the present study was to investigate the neuro-functional organization of reading in a patie... Read More
- Musical Expertise and Second Language Learning
Increasing evidence suggests that musical expertise influences brain organization and brain functions. Moreover, results at the behavioral and neurophysiological levels reveal that musical expertise p... Read More